Phosphorylation of Connexin43 on Serine368 by Protein Kinase C Regulates Gap Junctional Communication

Phorbol esters (e.g., TPA) activate protein kinase C (PKC), increase connexin43 (Cx43) phosphorylation, and decrease cell–cell communication via gap junctions in many cell types. We asked whether PKC directly phosphorylates and regulates Cx43. Rat epithelial T51B cells metabolically labeled with (32...

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Autores principales: Lampe, Paul D., TenBroek, Erica M., Burt, Janis M., Kurata, Wendy E., Johnson, Ross G., Lau, Alan F.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2000
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175134/
https://ncbi.nlm.nih.gov/pubmed/10871288
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