Tumor Necrosis Factor Induces Hyperphosphorylation of Kinesin Light Chain and Inhibits Kinesin-Mediated Transport of Mitochondria

The molecular motor kinesin is an ATPase that mediates plus end-directed transport of organelles along microtubules. Although the biochemical properties of kinesin are extensively studied, conclusive data on regulation of kinesin-mediated transport are largely lacking. Previously, we showed that the...

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Main Authors: De Vos, Kurt, Severin, Fedor, Van Herreweghe, Franky, Vancompernolle, Katia, Goossens, Vera, Hyman, Anthony, Grooten, Johan
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2000
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Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175118/
https://ncbi.nlm.nih.gov/pubmed/10851018
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