Tumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methylglyoxal-derived AGE

Tumor necrosis factor (TNF)-induced cell death in the fibrosarcoma cell line L929 is a caspase-independent process that is characterized by increased production of reactive oxygen species (ROS) in the mitochondria. To elucidate this ROS-dependent cell death pathway, a comparative study of the phosph...

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Bibliographische Detailangaben
Hauptverfasser: Van Herreweghe, Franky, Mao, Jianqiang, Chaplen, Frank W. R., Grooten, Johan, Gevaert, Kris, Vandekerckhove, Joël, Vancompernolle, Katia
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2002
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC117411/
https://ncbi.nlm.nih.gov/pubmed/11792832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012432399
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