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The Role of the Cooh Terminus of Sec2p in the Transport of Post-Golgi Vesicles

Sec2p is required for the polarized transport of secretory vesicles in S. cerevisiae. The Sec2p NH(2) terminus encodes an exchange factor for the Rab protein Sec4p. Sec2p associates with vesicles and in Sec2p COOH-terminal mutants Sec4p and vesicles no longer accumulate at bud tips. Thus, the Sec2p...

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Bibliografske podrobnosti
Main Authors: Elkind, N. Barry, Walch-Solimena, Christiane, Novick, Peter J.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175086/
https://ncbi.nlm.nih.gov/pubmed/10747090
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