The Viral Oncoprotein LMP1 Exploits TRADD for Signaling by Masking Its Apoptotic Activity

The tumor necrosis factor (TNF)-receptor 1–associated death domain protein (TRADD) mediates induction of apoptosis as well as activation of NF-κB by cellular TNF-receptor 1 (TNFR1). TRADD is also recruited by the latent membrane protein 1 (LMP1) oncoprotein of Epstein-Barr virus, but its role in LMP...

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Detalhes bibliográficos
Main Authors: Schneider, Frank, Neugebauer, Julia, Griese, Janine, Liefold, Nicola, Kutz, Helmut, Briseño, Cinthia, Kieser, Arnd
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174972/
https://ncbi.nlm.nih.gov/pubmed/18198944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060008
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