Schwann Cell Myelination Requires Timely and Precise Targeting of P(0) Protein

This report investigated mechanisms responsible for failed Schwann cell myelination in mice that overexpress P(0) (P(0) (tg)), the major structural protein of PNS myelin. Quantitative ultrastructural immunocytochemistry established that P(0) protein was mistargeted to abaxonal, periaxonal, and mesax...

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Main Authors: Yin, X., Kidd, G.J., Wrabetz, L., Feltri, M.L., Messing, A., Trapp, B.D.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2000
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174550/
https://ncbi.nlm.nih.gov/pubmed/10704450
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