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Dynein-Mediated Cargo Transport in Vivo: A Switch Controls Travel Distance

Cytoplasmic dynein is a microtubule-based motor with diverse cellular roles. Here, we use mutations in the dynein heavy chain gene to impair the motor's function, and employ biophysical measurements to demonstrate that cytoplasmic dynein is responsible for the minus end motion of bidirectionall...

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Bibliografische gegevens
Hoofdauteurs: Gross, Steven P., Welte, Michael A., Block, Steven M., Wieschaus, Eric F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174539/
https://ncbi.nlm.nih.gov/pubmed/10704445
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