Yeast Screens Identify the RNA Polymerase II CTD and SPT5 as Relevant Targets of BRCA1 Interaction

BRCA1 has been implicated in numerous DNA repair pathways that maintain genome integrity, however the function responsible for its tumor suppressor activity in breast cancer remains obscure. To identify the most highly conserved of the many BRCA1 functions, we screened the evolutionarily distant euk...

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Main Authors: Bennett, Craig B., Westmoreland, Tammy J., Verrier, Carmel S., Blanchette, Carrie A. B., Sabin, Tiffany L., Phatnani, Hemali P., Mishina, Yuliya V., Huper, Gudrun, Selim, Alice L., Madison, Ernest R., Bailey, Dominique D., Falae, Adebola I., Galli, Alvaro, Olson, John A., Greenleaf, Arno L., Marks, Jeffrey R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2008
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174531/
https://ncbi.nlm.nih.gov/pubmed/18197258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001448
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