Yeast Screens Identify the RNA Polymerase II CTD and SPT5 as Relevant Targets of BRCA1 Interaction

BRCA1 has been implicated in numerous DNA repair pathways that maintain genome integrity, however the function responsible for its tumor suppressor activity in breast cancer remains obscure. To identify the most highly conserved of the many BRCA1 functions, we screened the evolutionarily distant euk...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bennett, Craig B., Westmoreland, Tammy J., Verrier, Carmel S., Blanchette, Carrie A. B., Sabin, Tiffany L., Phatnani, Hemali P., Mishina, Yuliya V., Huper, Gudrun, Selim, Alice L., Madison, Ernest R., Bailey, Dominique D., Falae, Adebola I., Galli, Alvaro, Olson, John A., Greenleaf, Arno L., Marks, Jeffrey R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2008
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174531/
https://ncbi.nlm.nih.gov/pubmed/18197258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001448
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