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Combined Exposure to Anti-Androgens Exacerbates Disruption of Sexual Differentiation in the Rat

OBJECTIVE: The aim of this study was to assess whether the joint effects of three androgen receptor antagonists (vinclozolin, flutamide, procymidone) on male sexual differentiation after in utero and postnatal exposures can be predicted based on dose–response data of the individual chemicals. METHOD...

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Autori principali: Hass, Ulla, Scholze, Martin, Christiansen, Sofie, Dalgaard, Majken, Vinggaard, Anne Marie, Axelstad, Marta, Metzdorff, Stine Broeng, Kortenkamp, Andreas
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Institute of Environmental Health Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174404/
https://ncbi.nlm.nih.gov/pubmed/18174960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.9360
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