HIV, but not murine leukemia virus, vectors mediate high efficiency gene transfer into freshly isolated G(0)/G(1) human hematopoietic stem cells

Recent studies have opened the possibility that quiescent, G(0)/G(1) hematopoietic stem cells (HSC) can be gene transduced; lentiviruses (such as HIV type 1, HIV) encode proteins that permit transport of the viral genome into the nucleus of nondividing cells. We and others have recently demonstrated...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Uchida, Nobuko, Sutton, Richard E., Friera, Annabelle M., He, Dongping, Reitsma, Michael J., Chang, Wei Chun, Veres, Gabor, Scollay, Roland, Weissman, Irving L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21744/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9751769/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.20.11939
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!