HIV, but not murine leukemia virus, vectors mediate high efficiency gene transfer into freshly isolated G(0)/G(1) human hematopoietic stem cells

Recent studies have opened the possibility that quiescent, G(0)/G(1) hematopoietic stem cells (HSC) can be gene transduced; lentiviruses (such as HIV type 1, HIV) encode proteins that permit transport of the viral genome into the nucleus of nondividing cells. We and others have recently demonstrated...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Uchida, Nobuko, Sutton, Richard E., Friera, Annabelle M., He, Dongping, Reitsma, Michael J., Chang, Wei Chun, Veres, Gabor, Scollay, Roland, Weissman, Irving L.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1998
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21744/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9751769/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.20.11939
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