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Mutagenesis of the Phosphatidylinositol 4,5-Bisphosphate (Pip(2)) Binding Site in the Nh(2)-Terminal Domain of Ezrin Correlates with Its Altered Cellular Distribution
The cytoskeleton-membrane linker protein ezrin has been shown to associate with phosphatidyl-inositol 4,5-bisphosphate (PIP(2))-containing liposomes via its NH(2)-terminal domain. Using internal deletions and COOH-terminal truncations, determinants of PIP(2) binding were located to amino acids 12–11...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2174347/ https://ncbi.nlm.nih.gov/pubmed/11086008 |
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