Molecular Chaperones in the Yeast Endoplasmic Reticulum Maintain the Solubility of Proteins for Retrotranslocation and Degradation

Endoplasmic reticulum (ER)-associated degradation (ERAD) is the process by which aberrant proteins in the ER lumen are exported back to the cytosol and degraded by the proteasome. Although ER molecular chaperones are required for ERAD, their specific role(s) in this process have been ill defined. To...

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Autores principales: Nishikawa, Shuh-ichi, Fewell, Sheara W., Kato, Yoshihito, Brodsky, Jeffrey L., Endo, Toshiya
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2001
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174341/
https://ncbi.nlm.nih.gov/pubmed/11381090
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