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The Docking Stage of Yeast Vacuole Fusion Requires the Transfer of Proteins from a Cis-Snare Complex to a Rab/Ypt Protein

The homotypic fusion of yeast vacuoles requires Sec18p (NSF)-driven priming to allow vacuole docking, but the mechanism that links priming and docking is unknown. We find that a large multisubunit protein called the Vam2/6p complex is bound to cis-paired SNAP receptors (SNAREs) on isolated vacuoles....

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Библиографические подробности
Главные авторы: Price, Albert, Seals, Darren, Wickner, William, Ungermann, Christian
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2000
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174311/
https://ncbi.nlm.nih.gov/pubmed/10725336
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