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An Atp-Dependent, Ran-Independent Mechanism for Nuclear Import of the U1a and U2b′′ Spliceosome Proteins

Nuclear import of the two uracil-rich small nuclear ribonucleoprotein (U snRNP) components U1A and U2B′′ is mediated by unusually long and complex nuclear localization signals (NLSs). Here we investigate nuclear import of U1A and U2B′′ in vitro and demonstrate that it occurs by an active, saturable...

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Bibliografiske detaljer
Main Authors: Hetzer, Martin, Mattaj, Iain W.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174293/
https://ncbi.nlm.nih.gov/pubmed/10648562
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