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A Motif in the Clathrin Heavy Chain Required for the Hsc70/Auxilin Uncoating Reaction

The 70-kDa heat-shock cognate protein (Hsc70) chaperone is an ATP-dependent “disassembly enzyme” for many subcellular structures, including clathrin-coated vesicles where it functions as an uncoating ATPase. Hsc70, and its cochaperone auxilin together catalyze coat disassembly. Like other members of...

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Autores principales: Rapoport, Iris, Boll, Werner, Yu, Anan, Böcking, Till, Kirchhausen, Tom
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174180/
https://ncbi.nlm.nih.gov/pubmed/17978091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-09-0870
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