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Nuclear and cytoplasmic shuttling of TRADD induces apoptosis via different mechanisms

The adapter protein tumor necrosis factor receptor (TNFR)1–associated death domain (TRADD) plays an essential role in recruiting signaling molecules to the TNFRI receptor complex at the cell membrane. Here we show that TRADD contains a nuclear export and import sequence that allow shuttling between...

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Bibliografske podrobnosti
Main Authors: Morgan, Michael, Thorburn, Jacqueline, Pandolfi, Pier Paolo, Thorburn, Andrew
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174032/
https://ncbi.nlm.nih.gov/pubmed/12045187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200204039
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