A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response

The unfolded protein response (UPR) counteracts stress caused by unprocessed ER client proteins. A genome-wide survey showed impaired induction of many UPR target genes in xbp-1 mutant Caenorhabditis elegans that are unable to signal in the highly conserved IRE1-dependent UPR pathway. However a fami...

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Bibliographic Details
Main Authors: Urano, Fumihiko, Calfon, Marcella, Yoneda, Takunari, Yun, Chi, Kiraly, Moni, Clark, Scott G., Ron, David
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2002
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174003/
https://ncbi.nlm.nih.gov/pubmed/12186849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200203086
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