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Dual role for phosphoinositides in regulation of yeast and mammalian phospholipase D enzymes
Phospholipase D (PLD) generates lipid signals that coordinate membrane trafficking with cellular signaling. PLD activity in vitro and in vivo is dependent on phosphoinositides with a vicinal 4,5-phosphate pair. Yeast and mammalian PLDs contain an NH(2)-terminal pleckstrin homology (PH) domain that h...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173982/ https://ncbi.nlm.nih.gov/pubmed/12486109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200205056 |
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