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Identification of a phosphoinositide binding motif that mediates activation of mammalian and yeast phospholipase D isoenzymes.
Phosphoinositides are both substrates for second messenger-generating enzymes and spatially localized membrane signals that mediate vital steps in signal transduction, cytoskeletal regulation and membrane trafficking. Phosphatidylcholine-specific phospholipase D (PLD) activity is stimulated by phosp...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1999
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171657/ https://ncbi.nlm.nih.gov/pubmed/10545103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.21.5911 |
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