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Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1

Directed cell movement is a multi-step process requiring an initial spatial polarization that is established by asymmetric stimulation of Rho GTPases, phosphoinositides (PIs), and actin polymerization. We report that the Na-H exchanger isoform 1 (NHE1), a ubiquitously expressed plasma membrane ion e...

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Autori principali: Denker, Sheryl P., Barber, Diane L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173980/
https://ncbi.nlm.nih.gov/pubmed/12486114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200208050
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