Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli

Mitochondrial outer membrane permeabilization by proapoptotic Bcl-2 family proteins, such as Bax, plays a crucial role in apoptosis induction. However, whether this only causes the intracytosolic release of inducers of caspase-dependent death, such as cytochrome c, or also of caspase-independent dea...

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Bibliographic Details
Main Authors: Arnoult, Damien, Parone, Philippe, Martinou, Jean-Claude, Antonsson, Bruno, Estaquier, Jérôme, Ameisen, Jean Claude
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173976/
https://ncbi.nlm.nih.gov/pubmed/12486111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200207071
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