Complex of a protective antibody with its Ebola virus GP peptide epitope: unusual features of a Vλ(x)-light chain

13F6-1-2 is a murine monoclonal antibody that recognizes the heavily glycosylated mucin-like domain of the Ebola virus virion-attached glycoprotein (GP) and protects animals against lethal viral challenge. Here we present the crystal structure, at 2.0 Å, of 13F6-1-2 in complex with its Ebola virus G...

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Hauptverfasser: Lee, Jeffrey E., Kuehne, Ana, Abelson, Dafna M., Fusco, Marnie L., Hart, Mary Kate, Saphire, Erica Ollmann
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173910/
https://ncbi.nlm.nih.gov/pubmed/18005986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.10.017
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