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Elevated glucose inhibits VEGF-A–mediated endocardial cushion formation: modulation by PECAM-1 and MMP-2
Atrioventricular (AV) septal defects resulting from aberrant endocardial cushion (EC) formation are observed at increased rates in infants of diabetic mothers. EC formation occurs via an epithelial-mesenchymal transformation (EMT), involving transformation of endocardial cells into mesenchymal cells...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Rockefeller University Press
2003
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173755/ https://ncbi.nlm.nih.gov/pubmed/12591918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200209014 |
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