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MEKK3 initiates TGFβ2-dependent EMT during endocardial cushion morphogenesis

Congenital heart defects (CHDs) occur at a rate of five percent and are the most prevalent birth defects. A better understanding of the complex signaling networks regulating heart development is necessary to improve repair strategies for CHDs. The MAP3 kinase, MEKK3, is important to early embryogene...

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Detalhes bibliográficos
Main Authors: Stevens, Mark V., Broka, Derrick M., Parker, Patti, Rogowitz, Elisa, Vaillancourt, Richard R., Camenisch, Todd D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728220/
https://ncbi.nlm.nih.gov/pubmed/19008476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.180752
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