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MEKK3 initiates TGFβ2-dependent EMT during endocardial cushion morphogenesis
Congenital heart defects (CHDs) occur at a rate of five percent and are the most prevalent birth defects. A better understanding of the complex signaling networks regulating heart development is necessary to improve repair strategies for CHDs. The MAP3 kinase, MEKK3, is important to early embryogene...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728220/ https://ncbi.nlm.nih.gov/pubmed/19008476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.180752 |
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