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A tumor-associated β1 integrin mutation that abrogates epithelial differentiation control
SCC4 human keratinocytes are derived from a squamous cell carcinoma of the tongue and undergo very little spontaneous differentiation. Introduction of a wild-type β1 integrin subunit into SCC4 cells stimulates differentiation, suggesting either that the cells have a defect in the integrin signaling...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173744/ https://ncbi.nlm.nih.gov/pubmed/12578911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200209016 |
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