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Point mutations in EBV gH that abrogate or differentially affect B cell and epithelial cell fusion

Cell fusion mediated by Epstein-Barr virus requires three conserved glycoproteins, gB and gHgL, but activation is cell type specific. B cell fusion requires interaction between MHC-class II and a fourth virus glycoprotein, gp42, which complexes non-covalently with gHgL. Epithelial cell fusion requir...

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Detalhes bibliográficos
Main Authors: Wu, Liguo, Hutt-Fletcher, Lindsey M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965494/
https://ncbi.nlm.nih.gov/pubmed/17307213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.01.025
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