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Spindle checkpoint proteins Mad1 and Mad2 are required for cytostatic factor–mediated metaphase arrest
In cells containing disrupted spindles, the spindle assembly checkpoint arrests the cell cycle in metaphase. The budding uninhibited by benzimidazole (Bub) 1, mitotic arrest-deficient (Mad) 1, and Mad2 proteins promote this checkpoint through sustained inhibition of the anaphase-promoting complex/cy...
में बचाया:
| मुख्य लेखकों: | , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
The Rockefeller University Press
2003
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173727/ https://ncbi.nlm.nih.gov/pubmed/14691134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200306153 |
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