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A role for cytoplasmic dynein and LIS1 in directed cell movement

Cytoplasmic dynein has been implicated in numerous aspects of intracellular movement. We recently found dynein inhibitors to interfere with the reorientation of the microtubule cytoskeleton during healing of wounded NIH3T3 cell monolayers. We now find that dynein and its regulators dynactin and LIS1...

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Autores principales: Dujardin, Denis L., Barnhart, Lora E., Stehman, Stephanie A., Gomes, Edgar R., Gundersen, Gregg G., Vallee, Richard B.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173723/
https://ncbi.nlm.nih.gov/pubmed/14691133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200310097
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