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Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function

Mutations in the human LIS1 gene cause type I lissencephaly, a severe brain developmental disease involving gross disorganization of cortical neurons. In lower eukaryotes, LIS1 participates in cytoplasmic dynein-mediated nuclear migration. We previously reported that mammalian LIS1 functions in cell...

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Detalhes bibliográficos
Main Authors: Tai, Chin-Yin, Dujardin, Denis L., Faulkner, Nicole E., Vallee, Richard B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173479/
https://ncbi.nlm.nih.gov/pubmed/11889140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200109046
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