Tyrosine phosphorylation of type Iγ phosphatidylinositol phosphate kinase by Src regulates an integrin–talin switch

Engagement of integrin receptors with the extracellular matrix induces the formation of focal adhesions (FAs). Dynamic regulation of FAs is necessary for cells to polarize and migrate. Key interactions between FA scaffolding and signaling proteins are dependent on tyrosine phosphorylation. However,...

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Main Authors: Ling, Kun, Doughman, Renee L., Iyer, Vidhya V., Firestone, Ari J., Bairstow, Shawn F., Mosher, Deane F., Schaller, Michael D., Anderson, Richard A.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2003
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173703/
https://ncbi.nlm.nih.gov/pubmed/14691141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200310067
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