Cophosphorylation of amphiphysin I and dynamin I by Cdk5 regulates clathrin-mediated endocytosis of synaptic vesicles

It has been thought that clathrin-mediated endocytosis is regulated by phosphorylation and dephosphorylation of many endocytic proteins, including amphiphysin I and dynamin I. Here, we show that Cdk5/p35-dependent cophosphorylation of amphiphysin I and dynamin I plays a critical role in such process...

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Main Authors: Tomizawa, Kazuhito, Sunada, Satoshi, Lu, Yun-Fei, Oda, Yoshiya, Kinuta, Masahiro, Ohshima, Toshio, Saito, Taro, Wei, Fan-Yan, Matsushita, Masayuki, Li, Sheng-Tian, Tsutsui, Kimiko, Hisanaga, Shin-ichi, Mikoshiba, Katsuhiko, Takei, Kohji, Matsui, Hideki
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173686/
https://ncbi.nlm.nih.gov/pubmed/14623869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200308110
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