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Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels

A tumor-homing peptide, F3, selectively binds to endothelial cells in tumor blood vessels and to tumor cells. Here, we show that the cell surface molecule recognized by F3 is nucleolin. Nucleolin specifically bound to an F3 peptide affinity matrix from extracts of cultured breast carcinoma cells. An...

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Autori principali: Christian, Sven, Pilch, Jan, Akerman, Maria E., Porkka, Kimmo, Laakkonen, Pirjo, Ruoslahti, Erkki
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173679/
https://ncbi.nlm.nih.gov/pubmed/14638862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200304132
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