Conditional disruption of β1 integrin in Schwann cells impedes interactions with axons

In dystrophic mice, a model of merosin-deficient congenital muscular dystrophy, laminin-2 mutations produce peripheral nerve dysmyelination and render Schwann cells unable to sort bundles of axons. The laminin receptor and the mechanism through which dysmyelination and impaired sorting occur are unk...

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Hauptverfasser: Feltri, M. Laura, Porta, Diana Graus, Previtali, Stefano C., Nodari, Alessandro, Migliavacca, Barbara, Cassetti, Arianna, Littlewood-Evans, Amanda, Reichardt, Louis F., Messing, Albee, Quattrini, Angelo, Mueller, Ulrich, Wrabetz, Lawrence
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2002
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173589/
https://ncbi.nlm.nih.gov/pubmed/11777940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200109021
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