β1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination

Myelin is a multispiraled extension of glial membrane that surrounds axons. How glia extend a surface many-fold larger than their body is poorly understood. Schwann cells are peripheral glia and insert radial cytoplasmic extensions into bundles of axons to sort, ensheath, and myelinate them. Laminin...

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Bibliographische Detailangaben
Hauptverfasser: Nodari, Alessandro, Zambroni, Desirée, Quattrini, Angelo, Court, Felipe A., D'Urso, Alessandra, Recchia, Alessandra, Tybulewicz, Victor L.J., Wrabetz, Lawrence, Feltri, M. Laura
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2007
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064366/
https://ncbi.nlm.nih.gov/pubmed/17576799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200610014
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