β1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination

Myelin is a multispiraled extension of glial membrane that surrounds axons. How glia extend a surface many-fold larger than their body is poorly understood. Schwann cells are peripheral glia and insert radial cytoplasmic extensions into bundles of axons to sort, ensheath, and myelinate them. Laminin...

Full description

Saved in:
Bibliographic Details
Main Authors: Nodari, Alessandro, Zambroni, Desirée, Quattrini, Angelo, Court, Felipe A., D'Urso, Alessandra, Recchia, Alessandra, Tybulewicz, Victor L.J., Wrabetz, Lawrence, Feltri, M. Laura
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2007
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064366/
https://ncbi.nlm.nih.gov/pubmed/17576799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200610014
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items