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Sorting it out: AP-2 and alternate clathrin adaptors in endocytic cargo selection

The AP-2 adaptor complex is widely viewed as a linchpin molecule in clathrin-mediated endocytosis, simultaneously binding both clathrin and receptors. This dual interaction couples cargo capture with clathrin coat assembly, but it has now been discovered that the association with cargo is tightly re...

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Библиографические подробности
Главный автор: Traub, Linton M.
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2003
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173531/
https://ncbi.nlm.nih.gov/pubmed/14581447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200309175
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