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Impairment of LTD and cerebellar learning by Purkinje cell–specific ablation of cGMP-dependent protein kinase I

The molecular basis for cerebellar plasticity and motor learning remains controversial. Cerebellar Purkinje cells (PCs) contain a high concentration of cGMP-dependent protein kinase type I (cGKI). To investigate the function of cGKI in long-term depression (LTD) and cerebellar learning, we have gene...

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Bibliografski detalji
Glavni autori: Feil, Robert, Hartmann, Jana, Luo, Chongde, Wolfsgruber, Wiebke, Schilling, Karl, Feil, Susanne, Barski, Jaroslaw J., Meyer, Michael, Konnerth, Arthur, De Zeeuw, Chris I., Hofmann, Franz
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173527/
https://ncbi.nlm.nih.gov/pubmed/14568994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200306148
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