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A dual-functional paramyxovirus F protein regulatory switch segment: activation and membrane fusion

Many viral fusion–mediating glycoproteins couple α-helical bundle formation to membrane merger, but have different methods for fusion activation. To study paramyxovirus-mediated fusion, we mutated the SV5 fusion (F) protein at conserved residues L447 and I449, which are adjacent to heptad repeat (HR...

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Hlavní autoři: Russell, Charles J., Kantor, Karen L., Jardetzky, Theodore S., Lamb, Robert A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173521/
https://ncbi.nlm.nih.gov/pubmed/14581458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200305130
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