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Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
We studied the effect of microtubule-associated tau protein on trafficking of vesicles and organelles in primary cortical neurons, retinal ganglion cells, and neuroblastoma cells. Tau inhibits kinesin-dependent transport of peroxisomes, neurofilaments, and Golgi-derived vesicles into neurites. Loss...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Rockefeller University Press
2002
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173473/ https://ncbi.nlm.nih.gov/pubmed/11901170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200108057 |
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