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The cysteine-rich domain regulates ADAM protease function in vivo

ADAMs are membrane-anchored proteases that regulate cell behavior by proteolytically modifying the cell surface and ECM. Like other membrane-anchored proteases, ADAMs contain candidate “adhesive” domains downstream of their metalloprotease domains. The mechanism by which membrane-anchored cell surfa...

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Bibliografiske detaljer
Main Authors: Smith, Katherine M., Gaultier, Alban, Cousin, Helene, Alfandari, Dominique, White, Judith M., DeSimone, Douglas W.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173380/
https://ncbi.nlm.nih.gov/pubmed/12460986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200206023
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