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Translocation of the cytoplasmic domain of ADAM13 to the nucleus is essential for Calpain-8 expression and cranial neural crest cell migration

ADAMs are transmembrane metalloproteases that control cell behavior by cleaving both cell adhesion and signaling molecules. The cytoplasmic domain of ADAMs can regulate the proteolytic activity by controlling the subcellular localization and/or the activation of the protease domain. Here we show tha...

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Main Authors: Cousin, Hélène, Abbruzzese, Genevieve, Kerdavid, Erin, Gaultier, Alban, Alfandari, Dominique
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074609/
https://ncbi.nlm.nih.gov/pubmed/21316592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.12.009
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