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A mechanism of coupling RCC1 mobility to RanGTP production on the chromatin in vivo

The RanGTP gradient across the interphase nuclear envelope and on the condensed mitotic chromosomes is essential for many cellular processes, including nucleocytoplasmic transport and spindle assembly. Although the chromosome-associated enzyme RCC1 is responsible for RanGTP production, the mechanism...

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Detalhes bibliográficos
Main Authors: Li, Hoi Yeung, Wirtz, Denis, Zheng, Yixian
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173367/
https://ncbi.nlm.nih.gov/pubmed/12604592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200211004
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