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Wnt signaling promotes oncogenic transformation by inhibiting c-Myc–induced apoptosis
Aberrant activation of the Wnt/β-catenin signaling pathway is associated with numerous human cancers and often correlates with the overexpression or amplification of the c-myc oncogene. Paradoxical to the cellular transformation potential of c-Myc is its ability to also induce apoptosis. Using an in...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173296/ https://ncbi.nlm.nih.gov/pubmed/11980918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200201110 |
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