The integrin αvβ8 mediates epithelial homeostasis through MT1-MMP–dependent activation of TGF-β1

Întegrins, matrix metalloproteases (MMPs), and the cytokine TGF-β have each been implicated in homeostatic cell behaviors such as cell growth and matrix remodeling. TGF-β exists mainly in a latent state, and a major point of homeostatic control is the activation of TGF-β. Because the latent domain o...

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Bibliografische gegevens
Hoofdauteurs: Mu, Dezhi, Cambier, Stephanie, Fjellbirkeland, Lars, Baron, Jody L., Munger, John S., Kawakatsu, Hisaaki, Sheppard, Dean, Broaddus, V. Courtney, Nishimura, Stephen L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2002
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173277/
https://ncbi.nlm.nih.gov/pubmed/11970960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200109100
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