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Bloom's syndrome protein is required for correct relocalization of RAD50/MRE11/NBS1 complex after replication fork arrest

Bloom's syndrome (BS) is a rare genetic disorder characterized by a broad range of symptoms and, most importantly, a predisposition to many types of cancers. Cells derived from patients with BS exhibit an elevated rate of somatic recombination and hypermutability, supporting a role for bleomyci...

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Autori principali: Franchitto, Annapaola, Pichierri, Pietro
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173275/
https://ncbi.nlm.nih.gov/pubmed/11916980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200110009
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