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A cycle of Vam7p release from and PtdIns 3-P–dependent rebinding to the yeast vacuole is required for homotypic vacuole fusion

Vacuole fusion requires a coordinated cascade of priming, docking, and fusion. SNARE proteins have been implicated in the fusion itself, although their precise role in the cascade remains unclear. We now report that the vacuolar SNAP-23 homologue Vam7p is a mobile element of the SNARE complex, which...

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Autors principals: Boeddinghaus, Christine, Merz, Alexey J., Laage, Rico, Ungermann, Christian
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173272/
https://ncbi.nlm.nih.gov/pubmed/11916982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200112098
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