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Actin turnover is required to prevent axon retraction driven by endogenous actomyosin contractility

Growth cone motility and guidance depend on the dynamic reorganization of filamentous actin (F-actin). In the growth cone, F-actin undergoes turnover, which is the exchange of actin subunits from existing filaments. However, the function of F-actin turnover is not clear. We used jasplakinolide (jasp...

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Autors principals: Gallo, Gianluca, Yee, Hal F., Letourneau, Paul C.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173247/
https://ncbi.nlm.nih.gov/pubmed/12356866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200204140
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