Mesenchymal actomyosin contractility is required for androgen-driven urethral masculinization in mice

The morphogenesis of mammalian embryonic external genitalia (eExG) shows dynamic differences between males and females. In genotypic males, eExG are masculinized in response to androgen signaling. Disruption of this process can give rise to multiple male reproductive organ defects. Currently, mechan...

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Udgivet i:Commun Biol
Main Authors: Acebedo, Alvin R., Suzuki, Kentaro, Hino, Shinjiro, Alcantara, Mellissa C., Sato, Yuki, Haga, Hisashi, Matsumoto, Ken-ichi, Nakao, Mitsuyoshi, Shimamura, Kenji, Takeo, Toru, Nakagata, Naomi, Miyagawa, Shinichi, Nishinakamura, Ryuichi, Adelstein, Robert S., Yamada, Gen
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408527/
https://ncbi.nlm.nih.gov/pubmed/30886905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0336-3
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