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Adenovirus triggers macropinocytosis and endosomal leakage together with its clathrin-mediated uptake

Adenovirus type 2 (Ad2) binds the coxsackie B virus Ad receptor and is endocytosed upon activation of the α(v) integrin coreceptors. Here, we demonstrate that expression of dominant negative clathrin hub, eps15, or K44A-dynamin (dyn) inhibited Ad2 uptake into epithelial cells, indicating clathrin-de...

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Autors principals: Meier, Oliver, Boucke, Karin, Hammer, Silvija Vig, Keller, Stephan, Stidwill, Robert P., Hemmi, Silvio, Greber, Urs F.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173207/
https://ncbi.nlm.nih.gov/pubmed/12221069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200112067
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